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http://www.oliver-sinz.de/kontakt/ ">revatio patent extension Nevertheless, RTS,S is the first malaria candidate vaccine - and there have been many over the decades - to reach the stage of widespread testing at the most advanced phase of clinical trials. It is designed to prevent the Plasmodium parasite from infecting, maturing and multiplying in the liver, from where the parasite will re-enter the bloodstream to infect red blood cells and so cause symptoms.